Human Background Variation DataBase

hbvdb is a set of tools to handle the storage and exchange of genetic background frequencies.

It is specifically intended for genetic clinics and clinical genomics research groups, to catalogue variant frequencies in de-identified human exome or whole genome sequencing material.

The design allows the exclusion of particular phenotypes by simple tags, so that cases in one study can serve as controls in another, without violating personal integrity by storing complete genotypes. One can also add e.g. platform tags.

There are four components to this.

Daniel Nilsson (daniel.nilsson@ki.se), 2012-09-20

Clinical Genetics, Karolinska University Hospital
Department of Molecular Medicine and Surgery, Karolinska Institutet
Science for Life Laboratory, Stockholm

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